A hybrid stochastic-deterministic computational model accurately describes spatial dynamics and virus diffusion in HIV-1 growth competition assay

DOI10.1016/J.JTBI.2012.07.005MaRDI QIDQ293801zbMATH OpenOpenAlexWikidataFDO

Authors Taina Immonen, Richard L. Gibson, Thomas Leitner, Melanie A. Miller, Eric J. Arts, Erkki Somersalo, Daniela Calvetti

Publication date 9 June 2016

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2012.07.005

zbMATH Keywords

mathematical modelcellular automatonMarkov modelHIV-1 fitnessspatial inhomogeneity

Mathematics Subject Classification ID

Applications of Markov chains and discrete-time Markov processes on general state spaces (social mobility, learning theory, industrial processes, etc.) (60J20) Medical epidemiology (92C60) Computational methods for problems pertaining to biology (92-08)

Recommendations

• Modeling HIV-1 dynamics and fitness in cell culture across scales
• Modelling stochastic and deterministic behaviours in virus infection dynamics
• A stochastic spatio-temporal (SST) model to study cell-to-cell variability in HIV-1 infection
• Modeling and estimation of kinetic parameters and replicative fitness of HIV-1 from flow-cytometry-based growth competition experiments
• Spatially resolved modelling of immune responses following a multiscale approach: from computational implementation to quantitative predictions

Cites work

• A simple cellular automaton model for influenza A viral infections
• Incorporation of variability into the modeling of viral delays in HIV infection dynamics
• Modeling and estimation of kinetic parameters and replicative fitness of HIV-1 from flow-cytometry-based growth competition experiments
• Probing the effects of the well-mixed assumption on viral infection dynamics
• Spatial models of virus-immune dynamics

Cited in

(7)

• Asymptotic behaviors of a cell-to-cell HIV-1 infection model perturbed by white noise
• Modeling and estimation of kinetic parameters and replicative fitness of HIV-1 from flow-cytometry-based growth competition experiments
• Dynamics of a stochastic cell-to-cell HIV-1 model with distributed delay
• A stochastic spatio-temporal (SST) model to study cell-to-cell variability in HIV-1 infection
• Modeling HIV-1 dynamics and fitness in cell culture across scales
• Beyond the model limit: parameter inference across scales
• Spatially resolved modelling of immune responses following a multiscale approach: from computational implementation to quantitative predictions

This page was built for publication: A hybrid stochastic-deterministic computational model accurately describes spatial dynamics and virus diffusion in HIV-1 growth competition assay

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q293801)