Dose-Finding Based on Feasibility and Toxicity in T-cell Infusion Trials

DOI10.1111/j.0006-341X.2001.00914.xzbMath1209.62336WikidataQ52055389 ScholiaQ52055389MaRDI QIDQ3078842

Aniruddha Choudhury, Peter F. Thall, Hsi-Guang Sung

Publication date: 1 March 2011

Published in: Biometrics (Search for Journal in Brave)

zbMATH Keywords

leukemiacontinual reassessment methodphase I trialdose findingclinical trial designadoptive immunotherapymaximal tolerated doseT-cell infusion

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50)

Related Items

Adaptive clinical trial designs for phase I cancer studies

Uses Software

• QUADPACK

Cites Work

• Unnamed Item
• Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
• Continual Reassessment Method: A Likelihood Approach
• Implementing a random number package with splitting facilities
• A Strategy for Dose-Finding and Safety Monitoring Based on Efficacy and Adverse Outcomes in Phase I/II Clinical Trials
• Approaches for Optimal Sequential Decision Analysis in Clinical Trials