Adaptive clinical trial designs for phase I cancer studies
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Publication:2452091
DOI10.1214/14-SS106zbMATH Open1333.62286OpenAlexW1975592428MaRDI QIDQ2452091FDOQ2452091
Authors: Oleksandr Sverdlov, Weng Kee Wong, Yevgen Ryeznik 
Publication date: 30 May 2014
Published in: Statistics Surveys (Search for Journal in Brave)
Full work available at URL: https://projecteuclid.org/euclid.ssu/1401369114
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ethicscontinual reassessment methodmaximum tolerated doseup-and-down designsstochastic approximationoptimal designsphase IBayesian designstoxicityestimation efficiency``best intention designsdose finding studiesoncology trial designs
Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Sequential statistical design (62L05) Sequential statistical analysis (62L10) Stochastic approximation (62L20)
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Cited In (21)
- Bayesian models and decision algorithms for complex early phase clinical trials
- A new design of the continual reassessment method
- On optimal designs for clinical trials: an updated review
- A Bayesian phase I/II trial design for immunotherapy
- Improving the flexibility and efficiency of phase II designs for oncology trials
- PA‐CRM: A continuous reassessment method for pediatric phase I oncology trials with concurrent adult trials
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