Continual reassessment designs with early termination

DOI10.1093/BIOSTATISTICS/3.1.87zbMath1133.62366OpenAlexW2098980231WikidataQ46316138 ScholiaQ46316138MaRDI QIDQ5701130

John O'Quigley

Publication date: 2 November 2005

Published in: Biostatistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/biostatistics/3.1.87

zbMATH Keywords

Clinical trialSample sizeDose findingStopping rulesEarly terminationContinual reassessment methodPhase 1 designs

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Stopping times; optimal stopping problems; gambling theory (60G40) Optimal stopping in statistics (62L15)

Related Items (5)

A system for determining maximum tolerated dose in clinical trial ⋮ A new design of the continual reassessment method ⋮ Continual reassessment and related dose-finding designs ⋮ Adaptive clinical trial designs for phase I cancer studies ⋮ Unifying CRM and EWOC designs for phase I cancer clinical trials

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