A New Dose‐Finding Design for Bivariate Outcomes

DOI10.1111/j.0006-341X.2003.00115.xzbMath1274.62797OpenAlexW2059221883WikidataQ76350547 ScholiaQ76350547MaRDI QIDQ3433237

Anastasia Ivanova

Publication date: 27 April 2007

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1111/j.0006-341x.2003.00115.x

zbMATH Keywords

random walkdose-finding studiesup-and-down designphase I trialoptimal dose

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Related Items (12)

Optimizing the Concentration and Bolus of a Drug Delivered by Continuous Infusion ⋮ Bayesian models and decision algorithms for complex early phase clinical trials ⋮ Adaptive clinical trial designs for phase I cancer studies ⋮ Patient‐Specific Dose Finding Based on Bivariate Outcomes and Covariates ⋮ Utility-Based Optimization of Combination Therapy Using Ordinal Toxicity and Efficacy in Phase I/II Trials ⋮ Adaptive designs for dose-finding based on efficacy-toxicity response ⋮ Dose Finding for Continuous and Ordinal Outcomes with a Monotone Objective Function: A Unified Approach ⋮ Implementation of a Bayesian Design in a Dose‐Escalation Study of an Experimental Agent in Healthy Volunteers ⋮ Up-and-Down Designs for Selecting the Dose with Maximum Success Probability ⋮ Correlated endpoints: simulation, modeling, and extreme correlations ⋮ Penalized optimal designs for dose-finding ⋮ Bayesian Dose-Finding in Phase I/II Clinical Trials Using Toxicity and Efficacy Odds Ratios

Cites Work

• Dose Finding Using the Biased Coin Up-and-Down Design and Isotonic Regression
• Unnamed Item
• Unnamed Item

This page was built for publication: A New Dose‐Finding Design for Bivariate Outcomes