Up-and-Down Designs for Selecting the Dose with Maximum Success Probability
DOI10.1080/07474940701802034zbMATH Open1142.62049OpenAlexW2004490899MaRDI QIDQ5458029FDOQ5458029
Nancy Flournoy, Euloge E. Kpamegan
Publication date: 10 April 2008
Published in: Sequential Analysis (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1080/07474940701802034
Recommendations
dose-findingstochastic approximationMarkov chainsefficacyunimodalitytoxicitystationary treatment distributionphase I/II clinical trialrandom walk designsoptimal doseconstant gain stochastic algorithm
Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Sequential statistical design (62L05) Stochastic approximation (62L20)
Cites Work
- Dose-Finding Designs for HIV Studies
- A Strategy for Dose-Finding and Safety Monitoring Based on Efficacy and Adverse Outcomes in Phase I/II Clinical Trials
- A New Dose‐Finding Design for Bivariate Outcomes
- Title not available (Why is that?)
- A Method for Obtaining and Analyzing Sensitivity Data
- On a Stochastic Approximation Method
- Title not available (Why is that?)
- Stochastic Approximation
- Non-Parametric Up-and-down Experimentation
- A sequential design for maximizing the probability of a favourable response
- Some Results for Discrete Unimodality
- Asymptotic Distribution of Stochastic Approximation Procedures
- Optimal Designs for Bivariate Logistic Regression
- Properties of frequency distributions induced by general up-and-down methods for estimating quantiles
- Directed Walk Designs for Dose-Response Problems with Competing Failure Modes
- Toxicity in sequential dose-response experiments
Cited In (8)
- Up-and-down experiments of first and second order
- Sequential Implementation of Stepwise Procedures for Identifying the Maximum Tolerated Dose
- Adaptive designs for dose-finding based on efficacy-toxicity response
- Optimal designs and limiting optimal designs for a trinomial response
- An Optimizing Up-and-Down Design
- Up-and-down designs for dose-finding
- A novel technique for stochastic root-finding: enhancing the search with adaptive \(d\)-ary search
- Group up-and-down designs for dose-finding
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