scientific article; zbMATH DE number 1361709

zbMATH Open0926.62066MaRDI QIDQ4699451FDOQ4699451

Nancy Flournoy, Stephen D. Durham, A. Montazer-Haghighi

Publication date: 11 November 1999

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• scientific article; zbMATH DE number 1361708
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zbMATH Keywords

random walksdose-responsequantile targetingtoxicity study

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05) Optimal stopping in statistics (62L15)

Cited In (10)

• Up-and-down experiments of first and second order
• Operating characteristics of the standard phase I clinical trial design.
• The adaptive accelerated biased coin design for phase I clinical trials
• Derivation of Exact Distributions Following an Up-and-Down Design
• An Optimizing Up-and-Down Design
• Toxicity in sequential dose-response experiments
• Adaptive clinical trial designs for phase I cancer studies
• A sequential design for maximizing the probability of a favourable response
• Group up-and-down designs for dose-finding
• Up-and-Down Designs for Selecting the Dose with Maximum Success Probability

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