Dose Finding for Continuous and Ordinal Outcomes with a Monotone Objective Function: A Unified Approach

DOI10.1111/j.1541-0420.2008.01045.xzbMath1159.62334OpenAlexW1966316100WikidataQ42084799 ScholiaQ42084799MaRDI QIDQ93669

Se Hee Kim, Anastasia Ivanova, Sehee Kim, Anastasia Ivanova

Publication date: 13 May 2008

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1111/j.1541-0420.2008.01045.x

zbMATH Keywords

maximum tolerated doseup-and-down designscontinual reassessment methodphase I trials

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Related Items

Evaluation of phase I clinical trial designs for combinational agents along with guidance based on simulation studies, Adaptive isotonic estimation of the minimum effective and peak doses in the presence of covariates, Continual reassessment method with multiple toxicity constraints, On the consistency of the continual reassessment method with multiple toxicity constraints, Risk-Group-Specific Dose Finding Based on an Average Toxicity Score, The treatment versus experimentation dilemma in dose finding studies, UnifiedDoseFinding, A study of the probit model with latent variables in Phase I clinical trials

Uses Software

• R

Cites Work

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