A simple technique to evaluate model sensitivity in the continual reassessment method

DOI10.1111/J.0006-341X.2002.00671.XMaRDI QIDQ3079010zbMATH OpenWikidataFDO

Authors Ying Kuen Cheung, Rick Chappell

Publication date 1 March 2011

Published in Biometrics (Search for Journal in Brave)

zbMATH Keywords

continual reassessment methodindifference intervalmodel sensitivity

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Sequential statistical design (62L05)

Recommendations

• A note on the robustness of the continual reassessment method
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• Continual reassessment and related dose-finding designs
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Cites work

• A Curve‐Free Method for Phase I Clinical Trials
• Consistency of continual reassessment method under model misspecification
• Continual Reassessment Method: A Likelihood Approach
• Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
• Design and Analysis of Phase I Clinical Trials
• Sequential Designs for Phase I Clinical Trials with Late‐Onset Toxicities

Cited in

(15)

• Impact of different model structure and prior distribution in continual reassessment method
• A note on the robustness of the continual reassessment method
• The treatment versus experimentation dilemma in dose finding studies
• Statistical frameworks for oncology dose-finding designs with late-onset toxicities: a review
• Optimal sequential designs in phase I studies
• scientific article; zbMATH DE number 7370531 (Why is no real title available?)
• Continual reassessment method with multiple toxicity constraints
• A simulation-free approach to assessing the performance of the continual reassessment method
• Consistency of the when the curve is not monotone and its application to the POCRM
• Adaptive clinical trial designs for phase I cancer studies
• Dose Finding for Continuous and Ordinal Outcomes with a Monotone Objective Function: A Unified Approach
• On the consistency of the continual reassessment method with multiple toxicity constraints
• Continual reassessment and related dose-finding designs
• Stochastic approximation and modern model-based designs for dose-finding clinical trials
• Consistency of continual reassessment method under model misspecification

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