Continual reassessment method with multiple toxicity constraints

DOI10.1093/BIOSTATISTICS/KXQ062zbMATH Open1437.62521OpenAlexW2121660184WikidataQ33392065 ScholiaQ33392065MaRDI QIDQ3303685FDOQ3303685

Authors: Shing M. Lee, Bin Cheng, Ying Kuen Cheung 

Publication date: 4 August 2020

Published in: Biostatistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/biostatistics/kxq062

Recommendations

• On the consistency of the continual reassessment method with multiple toxicity constraints
• Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
• The Continual Reassessment Method for Multiple Toxicity Grades: A Bayesian Quasi‐Likelihood Approach
• Bayesian Model Averaging Continual Reassessment Method in Phase I Clinical Trials
• Designs foe phase i cancer clinical trials with differentiation of graded toxicity

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
• A simple technique to evaluate model sensitivity in the continual reassessment method
• Coherence principles in dose-finding studies
• The Continual Reassessment Method for Multiple Toxicity Grades: A Bayesian Quasi‐Likelihood Approach
• Dose-Finding Based on Multiple Toxicities in a Soft Tissue Sarcoma Trial
• Dose Finding for Continuous and Ordinal Outcomes with a Monotone Objective Function: A Unified Approach
• A Random Walk Rule for Phase I Clinical Trials
• Stochastic approximation with virtual observations for dose-finding on discrete levels
• On the Use of Nonparametric Curves in Phase I Trials with Low Toxicity Tolerance
• Sequential Implementation of Stepwise Procedures for Identifying the Maximum Tolerated Dose
• Risk-group-specific dose finding based on an average toxicity score

Cited In (10)

• Designs foe phase i cancer clinical trials with differentiation of graded toxicity
• Time-to-event continual reassessment method incorporating treatment cycle information with application to an oncology phase I trial
• A continual reassessment method without undue risk of toxicity
• A generalized calibrated Bayesian hierarchical modeling approach to basket trials with multiple endpoints
• Incorporating patient-reported outcomes in dose-finding clinical trials
• Bayesian modeling of a bivariate toxicity outcome for early phase oncology trials evaluating dose regimens
• Application of the patient-reported outcomes continual reassessment method to a phase I study of radiotherapy in endometrial cancer
• Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
• On the consistency of the continual reassessment method with multiple toxicity constraints
• A phase I dose-finding study based on polychotomous toxicity responses

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