A Random Walk Rule for Phase I Clinical Trials

From MaRDI portal
Publication:4349992

DOI10.2307/2533975zbMath0877.62075OpenAlexW2152155324WikidataQ73436225 ScholiaQ73436225MaRDI QIDQ4349992

Nancy Flournoy, William F. Rosenberger, Stephen D. Durham

Publication date: 27 August 1997

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://semanticscholar.org/paper/724fae826be4426069dbe377ed74456475e8db3d




Related Items (26)

Designs for Single- or Multiple-Agent Phase I TrialsAn application of reinforced urn processes to determining maximum tolerated doseSequential design for binary dose-response experimentsA Latent Contingency Table Approach to Dose Finding for Combinations of Two AgentsA new design of the continual reassessment methodInformation in a two-stage adaptive optimal designStochastic approximation and modern model-based designs for dose-finding clinical trialsA new look at evaluating MTD designs in cancer researchAdaptive clinical trial designs for phase I cancer studiesContinual reassessment method with multiple toxicity constraintsOn the consistency of the continual reassessment method with multiple toxicity constraintsSimple benchmark for complex dose finding studiesUp-and-down experiments of first and second orderSequential Designs for Phase I Clinical Trials with Late‐Onset ToxicitiesGroup up-and-down designs for dose-findingStatistical Properties of a Modified Accelerated Design for Phase I Cancer Clinical TrialsDose Finding Using the Biased Coin Up-and-Down Design and Isotonic RegressionBayesian Optimal Designs for Phase I Clinical TrialsOn optimal designs for clinical trials: an updated reviewDerivation of Exact Distributions Following an Up-and-Down DesignIndividualized dosing for multiple ordered groups of patientsOperating characteristics of the standard phase I clinical trial design.Randomized group up and down experimentsProperties of frequency distributions induced by general up-and-down methods for estimating quantilesA sequential design for maximizing the probability of a favourable responseA conversation with Nancy Flournoy




This page was built for publication: A Random Walk Rule for Phase I Clinical Trials