Bayesian decision procedures based on logistic regression models for dose-finding studies

DOI10.1080/10543409808835252zbMath0957.62005OpenAlexW2018996306WikidataQ52236036 ScholiaQ52236036MaRDI QIDQ4512851

David J. Williamson, John Whitehead

Publication date: 29 March 2001

Published in: Journal of Biopharmaceutical Statistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/10543409808835252

zbMATH Keywords

clinical trialslogistic regressionmaximum tolerated dosecontinual reassessment methoddose escalation

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Bayesian problems; characterization of Bayes procedures (62C10)

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Optimal sampling for repeated binary measurements ⋮ Information in a two-stage adaptive optimal design ⋮ A Review of Modern Computational Algorithms for Bayesian Optimal Design ⋮ A Bayesian adaptive dose-finding algorithm for balancing individual- and population-level ethics in Phase I clinical trials ⋮ Continual reassessment and related dose-finding designs ⋮ Adaptive Bayesian compound designs for dose finding studies ⋮ Adaptive clinical trial designs for phase I cancer studies ⋮ Book Reviews ⋮ Sequential Designs for Dose Escalation Studies in Oncology ⋮ Retrospective Analysis of Sequential Dose‐Finding Designs ⋮ Adaptive designs for selecting drug combinations based on efficacy-toxicity response ⋮ Theoretical study of the continual reassessment method ⋮ Adaptive designs for dose-finding based on efficacy-toxicity response ⋮ Simulation-based sequential Bayesian design ⋮ Implementation of a Bayesian Design in a Dose‐Escalation Study of an Experimental Agent in Healthy Volunteers

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