scientific article; zbMATH DE number 524373

MaRDI QIDQ4284864zbMATH OpenFDO

Authors Stephen D. Durham, Nancy Flournoy

Publication date 19 May 1994

zbMATH Keywords

biased coin rulegenerating new discrete probability distribution functionslogistic response functionquantile estimationresponse functionsequential treatment allocationstationary treatment distributions

Mathematics Subject Classification ID

Sums of independent random variables; random walks (60G50) Sequential estimation (62L12)

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Cited in

(24)

• Penalized optimal designs for dose-finding
• Randomized group up and down experiments
• Operating characteristics of the standard phase I clinical trial design.
• Properties of frequency distributions induced by general up-and-down methods for estimating quantiles
• Random walk density function with unknown origin
• Asymptotic normality of maximum likelihood estimators from multiparameter response-driven designs
• Escalation with overdose control using ordinal toxicity grades for cancer phase I clinical trials
• Adaptive clinical trial designs for phase I cancer studies
• Cumulative cohort design for dose-finding
• Optimal adaptive generalized Pólya urn design for multi-arm clinical trials
• Up-and-down experiments of first and second order
• Group up-and-down designs for dose-finding
• A conversation with Nancy Flournoy
• Sequential design for binary dose-response experiments
• scientific article; zbMATH DE number 1218930 (Why is no real title available?)
• scientific article; zbMATH DE number 1276017 (Why is no real title available?)
• A Random Walk Rule for Phase I Clinical Trials
• Incorporating a patient dichotomous characteristic in cancer phase I clinical trials using escalation with overdose control
• Gap statistics close to the quantile of a random walk
• An optimizing up-and-down design
• Bias induced by adaptive dose-finding designs
• Conditional information and inference in response-adaptive allocation designs
• A semi-Markov process for the K-in-a-Row design
• Design efficiency in dose finding studies

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