One-Sided Tests in Clinical Trials with Multiple Endpoints

DOI10.1111/J.0006-341X.2001.01039.XzbMath1209.62229WikidataQ46896288 ScholiaQ46896288MaRDI QIDQ3078858

Tze Leung Lai, Pascale Tubert-Bitter, Daniel Bloch

Publication date: 1 March 2011

Published in: Biometrics (Search for Journal in Brave)

zbMATH Keywords

indifference zonebootstrap testsmultivariate responseefficacy and toxicity

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Testing in survival analysis and censored data (62N03)

Related Items (5)

Approval policies for modifications to machine learning‐based software as a medical device: A study of bio‐creep ⋮ Nonparametric directional testing for multivariate problems in conjunction with a closed testing principle ⋮ Some improved tests for multivariate one-sided hypotheses ⋮ Adaptive Design and Estimation in Randomized Clinical Trials with Correlated Observations ⋮ Complementary hypotheses in safety surveillance

Cites Work

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• Testing Hypotheses About an Identified Treatment When There are Multiple Endpoints
• Resampling methods for confidence intervals in group sequential trials
• Group Sequential Tests for Bivariate Response: Interim Analyses of Clinical Trials with Both Efficacy and Safety Endpoints
• Exact t and F Tests for Analyzing Studies with Multiple Endpoints
• Monotone Discriminant Functions and Their Applications in Rheumatology
• On The Design and Analysis of Randomized Clinical Trials with Multiple Endpoints
• One-Sided Testing Problems in Multivariate Analysis
• A multivariate analogue of the one-sided test
• The bootstrap and Edgeworth expansion

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