Scan statistics on Poisson random fields with applications in genomics

DOI10.1214/15-AOAS892zbMath1400.62300arXiv1406.3258MaRDI QIDQ312915

Benjamin Yakir, Li C. Xia, Nancy R. Zhang, David O. Siegmund

Publication date: 9 September 2016

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1406.3258

zbMATH Keywords

Poisson processesscan statisticschange-point detectionnext-generation sequencingstructural variation

Mathematics Subject Classification ID

Random fields; image analysis (62M40) Classification and discrimination; cluster analysis (statistical aspects) (62H30) Applications of statistics to biology and medical sciences; meta analysis (62P10) Protein sequences, DNA sequences (92D20)

Related Items

Scan statistics on Poisson random fields with applications in genomics, Translocation Detection from Hi-C Data via Scan Statistics, Multidimensional multiscale scanning in exponential families: limit theory and statistical consequences, Segmentation and estimation of change-point models: false positive control and confidence regions

Uses Software

• seqCBS
• Delly
• Pindel

Cites Work

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• Scan statistics on Poisson random fields with applications in genomics
• Change-point model on nonhomogeneous Poisson processes with application in copy number profiling by next-generation DNA sequencing
• Detecting simultaneous variant intervals in aligned sequences
• The statistics of gene mapping
• Statistical composition of high-scoring segments from molecular sequences
• Sequential analysis. Tests and confidence intervals
• The admixture model in linkage analysis
• Testing for a signal with unknown location and scale in a stationary Gaussian random field
• Multiple testing of local maxima for detection of peaks in ChIP-Seq data
• Extremes in Random Fields
• False discovery rate for scanning statistics
• A spatial scan statistic
• Tail Approximations for Maxima of Random Fields by Likelihood Ratio Transformations
• Random Fields and Geometry
• Scan Statistics With Weighted Observations
• Mapping quantitative trait loci in oligogenic models