Optimisation of strain selection in evolutionary continuous culture

DOI10.1080/00207179.2016.1264631MaRDI QIDQ3133016zbMATH OpenOpenAlexFDO

Authors Térence Bayen, Francis Mairet

Publication date 12 February 2018

Published in International Journal of Control (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/00207179.2016.1264631

zbMATH Keywords

optimal feedbackchemostat modelPontryagin maximum principlesingular controlprocess controlbiotechnology

Mathematics Subject Classification ID

Population dynamics (general) (92D25) Optimality conditions for problems involving ordinary differential equations (49K15) Variational principles of physics (49S05) Optimal feedback synthesis (49N35)

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(4)

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• The continuous morbidostat: a chemostat with controlled drug application to select for drug resistance mutants
• Stabilization of the chemostat system with mutations and application to microbial production
• \textit{Turnpike} features in optimal selection of species represented by quota models

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