From statistical power to statistical assurance: it's time for a paradigm change in clinical trial design

DOI10.1080/03610918.2016.1259476MaRDI QIDQ3133065zbMATH OpenOpenAlexFDO

Authors Ding-Geng (Din) Chen, Shuyen Ho

Publication date 12 February 2018

Published in Communications in Statistics. Simulation and Computation (Search for Journal in Brave)

Full work available at URL http://hdl.handle.net/2263/64065

zbMATH Keywords

sample size determinationstatistical powerMonte Carlo simulationassuranceBayesian prior distributionconditional and unconditional probability

Mathematics Subject Classification ID

Parametric hypothesis testing (62F03) Bayesian inference (62F15) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

• Exact statistical power for response adaptive designs
• Utilities of the \(P\)-value distribution associated with effect size in clinical trials
• Optimal Conditional Error Functions for the Control of Conditional Power
• Generalized Likelihood Ratio Statistics and Uncertainty Adjustments in Efficient Adaptive Design of Clinical Trials
• A sample size adjustment procedure for clinical trials based on conditional power

Cited in

(5)

• Bayesian Approach for Joint Modeling Longitudinal Data and Survival Data Simultaneously in Public Health Studies
• Exact sample size determination for a single Poisson random sample
• Bayesian sample size determination for diagnostic accuracy studies
• Utilities of the \(P\)-value distribution associated with effect size in clinical trials
• Applying generalized funnel plots to help design statistical analyses

This page was built for publication: From statistical power to statistical assurance: it's time for a paradigm change in clinical trial design

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q3133065)