Generalized Likelihood Ratio Statistics and Uncertainty Adjustments in Efficient Adaptive Design of Clinical Trials
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Publication:3527716
DOI10.1080/07474940802241009zbMath1147.62066arXiv1105.4667MaRDI QIDQ3527716
Publication date: 30 September 2008
Published in: Sequential Analysis (Search for Journal in Brave)
Full work available at URL: https://arxiv.org/abs/1105.4667
tables; Kullback-Leibler information; sample size re-estimation; multiparameter exponential family; internal pilot; Hoeffding's information bound; modified Haybittle-Peto test
62P10: Applications of statistics to biology and medical sciences; meta analysis
62L10: Sequential statistical analysis
62N03: Testing in survival analysis and censored data
62F05: Asymptotic properties of parametric tests
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