Power, sample size and adaptation considerations in the design of group sequential clinical trials

DOI10.1093/BIOMET/91.3.507MaRDI QIDQ3429959zbMATH OpenOpenAlexFDO

Authors Tze Leung Lai, Mei-Chiung Shih

Publication date 20 March 2007

Published in Biometrika (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1093/biomet/91.3.507

zbMATH Keywords

futility boundarygroup sequential testinformation bound

Mathematics Subject Classification ID

Sequential statistical design (62L05) Optimal stopping in statistics (62L15) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited in

(17)

• Most powerful test sequences with early stopping options
• Group-sequential logrank methods for trial designs using bivariate non-competing event-time outcomes
• Asymptotically optimal multistage tests of simple hypotheses
• Active postmarketing drug surveillance for multiple adverse events
• Generalized Sequential Probability Ratio Test for Separate Families of Hypotheses
• Generalized Likelihood Ratio Statistics and Uncertainty Adjustments in Efficient Adaptive Design of Clinical Trials
• Semiparametric Efficiency and Its Implication on the Design and Analysis of Group-Sequential Studies
• Efficient adaptive randomization and stopping rules in multi-arm clinical trials for testing a new treatment
• Modern sequential analysis and its applications to computerized adaptive testing
• Complementary hypotheses in safety surveillance
• Bandit Theory: Applications to Learning Healthcare Systems and Clinical Trials
• Adaptive and nonadaptive group sequential tests
• Asymptotically Optimal Sequential Design for Rank Aggregation
• Beyond boundaries: Gary Lorden’s groundbreaking contributions to sequential analysis
• Asymptotically optimal multistage tests for non-i.i.d. data
• Adaptive enrichment designs for confirmatory trials
• A new approach to designing phase I-II cancer trials for cytotoxic chemotherapies

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