Testing genetic association in pair-matched case-control design by incorporating Hardy-Wein\-berg disequilibrium

MaRDI QIDQ3170140zbMATH OpenFDO

Authors Min Yuan, Jinfeng Xu

Publication date 29 September 2011

zbMATH Keywords

conditional inferencegenetic model selectionmaximum efficiency robustness

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Nonparametric robustness (62G35) Applications of statistics to biology and medical sciences; meta analysis (62P10) Monte Carlo methods (65C05) Genetics and epigenetics (92D10)

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Cited in

(5)

• Asymptotic powers for matched trend tests and robust matched trend tests in case-control genetic association studies
• Exploring case-control genetic association tests using phase diagrams
• Examining the rare disease assumption used to justify HWE testing with control samples
• A model-embedded trend test with incorporating Hardy-Weinberg equilibrium information
• Comparison of statistical methods in testing of Hardy-Weinberg equilibrium in case-control genetic association studies

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