Power gains by using external information in clinical trials are typically not possible when requiring strict type I error control

DOI10.1002/BIMJ.201800395zbMATH Open1436.62583OpenAlexW2953905579WikidataQ91550189 ScholiaQ91550189MaRDI QIDQ3299104FDOQ3299104

Authors: Annette Kopp-Schneider, Silvia Calderazzo, Manuel Wiesenfarth 

Publication date: 17 July 2020

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.201800395

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zbMATH Keywords

evidence synthesishistorical informationBayesian dynamic borrowing of informationfrequentist error controlrobust prior

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cited In (5)

• A frequentist approach to dynamic borrowing
• On the relevance of prognostic information for clinical trials: A theoretical quantification
• Monotonicity conditions for avoiding counterintuitive decisions in basket trials
• Robust incorporation of historical information with known type I error rate inflation
• Increasing the efficiency of randomized trial estimates via linear adjustment for a prognostic score

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