Power gains by using external information in clinical trials are typically not possible when requiring strict type I error control
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Publication:3299104
Recommendations
- Dynamic borrowing through empirical power priors that control type I error
- Elastic priors to dynamically borrow information from historical data in clinical trials
- Hierarchical commensurate and power prior models for adaptive incorporation of historical information in clinical trials
- scientific article; zbMATH DE number 1222379
- Incorporating historical information in biosimilar trials: challenges and a hybrid Bayesian-frequentist approach
Cited in
(8)- Monotonicity conditions for avoiding counterintuitive decisions in basket trials
- On the relevance of prognostic information for clinical trials: A theoretical quantification
- A frequentist approach to dynamic borrowing
- Robust incorporation of historical information with known type I error rate inflation
- Increasing the efficiency of randomized trial estimates via linear adjustment for a prognostic score
- Augmenting treatment arms with external data through propensity-score weighted power priors: an application in expanded access
- Statistical modeling to adjust for time trends in adaptive platform trials utilizing non-concurrent controls
- Modified conditional borrowing-by-part power prior for dynamic and parameter-specific information borrowing of the Gaussian endpoint
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