Assessing the diagnostic power of variables measured with a detection limit

DOI10.1007/S00180-015-0628-0MaRDI QIDQ333355zbMATHOpenAlexFDO

Authors Bochao Jia, Yuan-chin Ivan Chang, Zhanfeng Wang

Publication date 28 October 2016

Published in Computational Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/s00180-015-0628-0

zbMATH Keywords

AUCROC curvelimit of detectionpartial AUC

Mathematics Subject Classification ID

Computational methods for problems pertaining to statistics (62-08) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

• ROC curve inference for best linear combination of two biomarkers subject to limits of detection
• Maximum Likelihood Ratio Tests for Comparing the Discriminatory Ability of Biomarkers Subject to Limit of Detection
• Youden index and optimal cut-point estimated from observations affected by a lower limit of detection
• Partial AUC Estimation and Regression
• Receiver Operating Characteristic Studies and Measurement Errors

Cites work

• Advances in Neural Networks – ISNN 2005
• Marker selection via maximizing the partial area under the ROC curve of linear risk scores
• Maximum Likelihood Ratio Tests for Comparing the Discriminatory Ability of Biomarkers Subject to Limit of Detection
• Pooling biospecimens and limits of detection: effects on ROC curve analysis
• ROC curve inference for best linear combination of two biomarkers subject to limits of detection
• Regression analysis for the partial area under the ROC curve

Cited in

(1)

• Analysis of a marker for cancer of the thyroid with a limit of detection

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Uses Software

• UCI

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