Pooling biospecimens and limits of detection: effects on ROC curve analysis

DOI10.1093/biostatistics/kxj027zbMath1170.62395OpenAlexW2121545841WikidataQ58322556 ScholiaQ58322556MaRDI QIDQ3434168

Sunni L. Mumford, Enrique F. Schisterman, Albert Vexler, Aiyi Liu

Publication date: 23 April 2007

Published in: Biostatistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/biostatistics/kxj027

zbMATH Keywords

Maximum likelihoodSamplingPooling designLimit of detectionReceiver operating characteristics

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Estimation in survival analysis and censored data (62N02)

Related Items (13)

Pooling Designs for Outcomes under a Gaussian Random Effects Model ⋮ Assessing the diagnostic power of variables measured with a detection limit ⋮ Estimating covariate-adjusted measures of diagnostic accuracy based on pooled biomarker assessments ⋮ Single-index regression for pooled biomarker data ⋮ Nonparametric-likelihood inference based on cost-effectively-sampled-data ⋮ Cost-efficient designs based on linearly associated biomarkers ⋮ Maximum Likelihood Ratio Tests for Comparing the Discriminatory Ability of Biomarkers Subject to Limit of Detection ⋮ Binary Regression Analysis with Pooled Exposure Measurements: A Regression Calibration Approach ⋮ Smooth ROC curves and surfaces for markers subject to a limit of detection using monotone natural cubic splines ⋮ Nonparametric deconvolution of density estimation based on observed sums ⋮ Review of statistical analyses in drug discovery and chemogenomics ⋮ Case-control data analysis for randomly pooled biomarkers ⋮ A combined efficient design for biomarker data subject to a limit of detection due to measuring instrument sensitivity

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