An Efficient R-Estimator for the ED50

DOI10.2307/2288352MaRDI QIDQ3339991zbMATH OpenOpenAlexFDO

Authors Barry R. James, Kang Ling James, Henrique Westenberger

Publication date 1984

Published in Journal of the American Statistical Association (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2307/2288352

zbMATH Keywords

Asymptotic distributionssmall-sample behaviormedian effective dosequantal bioassaysymmetric tolerance distributionAnalogues of R-estimatorsestimating the medianlogistic scores estimatorSpearman-Kärbertrimmed Spearman-Kärber

Mathematics Subject Classification ID

Nonparametric estimation (62G05) Asymptotic properties of nonparametric inference (62G20) Applications of statistics to biology and medical sciences; meta analysis (62P10) Monte Carlo methods (65C05)

Recommendations

• Discrete Delta Estimation of the Variance of the Logistic Scores Estimator of ED50
• Consistency and asymptotic normality of the estimated effective doses in bioassay
• Asymptotic properties of \=w, an estimator of the ED50 suggested for use in up-and-down experiments in bio-assay
• Robust and efficient estimation of effective dose
• A finite sample comparison of nonparametric estimates of the effective dose in quantal bioassay

Cited in

(2)

• Nonparametric estimation of dose-response curves with application to ED50 estimation
• Consistency and asymptotic normality of the estimated effective doses in bioassay

This page was built for publication: An Efficient R-Estimator for the ED50

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q3339991)