Nonparametric estimation of dose-response curves with application to ED50 estimation

DOI10.1080/00949658708811004zbMATH Open0622.62102OpenAlexW2083958979MaRDI QIDQ3759779FDOQ3759779

Authors: Russell F. Kappenman 

Publication date: 1987

Published in: Journal of Statistical Computation and Simulation (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/00949658708811004

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• Kernel and Probit Estimates in Quantal Bioassay
• A Note on Nonparametric Estimation of the Effective Dose in Quantal Bioassay
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• A finite sample comparison of nonparametric estimates of the effective dose in quantal bioassay

zbMATH Keywords

cross-validationrobust estimationkernel estimatorsample reusesimulation studiesED 50median effective dosedose response curve estimation proceduretrimmed Spearman-Kärber estimation

Mathematics Subject Classification ID

Nonparametric estimation (62G05) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• Title not available (Why is that?)
• Robust estimators for quantal bioassay
• A nonparametric data based univariate density function estimate
• An Efficient R-Estimator for the ED50

Cited In (12)

• Interval estimation of the \(ED_{50}\) when a logistic dose-response curve is incorrectly assumed
• On the Use of Nonparametric Curves in Phase I Trials with Low Toxicity Tolerance
• A finite sample comparison of nonparametric estimates of the effective dose in quantal bioassay
• Sigmoidally Constrained Maximum Likelihood Estimation in Quantal Bioassay
• A Note on Nonparametric Estimation of the Effective Dose in Quantal Bioassay
• Parametric and nonparametric estimators of ED100α
• Consistency and asymptotic normality of the estimated effective doses in bioassay
• A survey of literature on quantal response curves with a view toward application to the problem of selecting the curve with the smallest q-quantile (ediooq)
• Choice of Number of Doses for Maximum Likelihood Estimation of the ED50 for Quantal Dose-Response Data
• Kernel Estimates of Dose Response
• Selection of number of dose levels and its robustness for binary response data
• Monotone B-Spline Smoothing for a Generalized Linear Model Response

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