Parameter identification for the Landau-Lifshitz-Gilbert equation in magnetic particle imaging
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Publication:3379574
Biomedical imaging and signal processing (92C55) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Integro-partial differential equations (35R09) Inverse problems for PDEs (35R30) Inverse problems (including inverse scattering) in optics and electromagnetic theory (78A46) Statistical mechanics of magnetic materials (82D40) Physiological flow (92C35) Cell biology (92C37) System identification (93B30) Statistical mechanics of nanostructures and nanoparticles (82D80)
Abstract: Magnetic particle imaging (MPI) is a tracer-based technique for medical imaging where the tracer consists of ironoxide nanoparticles. The key idea is to measure the particle response to a temporally changing external magnetic field to compute the spatial concentration of the tracer inside the object. A decent mathematical model demands for a data-driven computation of the system function which does not only describe the measurement geometry but also encodes the interaction of the particles with the external magnetic field. The physical model of this interaction is given by the Landau-Lifshitz-Gilbert (LLG) equation. The determination of the system function can be seen as an inverse problem of its own which can be interpreted as a calibration problem for MPI. In this contribution the calibration problem is formulated as an inverse parameter identification problem for the LLG equation. We give a detailed analysis of the direct as well as the inverse problem in an all-at-once as well as in a reduced setting. The analytical results yield a deeper understanding of inverse problems connected to the LLG equation and provide a starting point for the development of robust numerical solution methods in MPI.
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