Mathematical models for magnetic particle imaging

DOI10.1088/1361-6420/AAC535zbMATH Open1395.78271arXiv1803.07408OpenAlexW2791846943MaRDI QIDQ4571018FDOQ4571018

Authors: Tobias Kluth 

Publication date: 6 July 2018

Published in: Inverse Problems (Search for Journal in Brave)

Abstract: Magnetic particle imaging (MPI) is a relatively new imaging modality. The nonlinear magnetization behavior of nanoparticles in an applied magnetic field is employed to reconstruct an image of the concentration of nanoparticles. Finding a sufficiently accurate model for the particle behavior is still an open problem. For this reason the reconstruction is still computed using a measured forward operator which is obtained in a time-consuming calibration process. The state of the art model used for the imaging methodology and first model-based reconstructions relies on strong model simplifications which turned out to cause too large modeling errors. Neglecting particle-particle interactions, the forward operator can be expressed by a Fredholm integral operator of the first kind describing the inverse problem. In this article we give an overview of relevant mathematical models which have not been investigated theoretically in the context of inverse problems yet. We consider deterministic models which are based on the physical behavior including relaxation mechanisms affecting the particle magnetization. The behavior of the models is illustrated with numerical simulations for monodisperse as well as polydisperse tracer. We further motivate linear and nonlinear problems beyond the solely concentration reconstruction related to applications. This model survey complements a recent topical review on MPI [30] and builds the basis for upcoming theoretical as well as empirical investigations.

Full work available at URL: https://arxiv.org/abs/1803.07408

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zbMATH Keywords

magnetic particle imagingparticle dynamicsmodel review

Mathematics Subject Classification ID

Technical applications of optics and electromagnetic theory (78A55) Biomedical imaging and signal processing (92C55) Integral operators (45P05) Research exposition (monographs, survey articles) pertaining to optics and electromagnetic theory (78-02)

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Cited In (14)

• Parameter Identification for the Landau–Lifshitz–Gilbert Equation in Magnetic Particle Imaging
• Mathematical methods for restoration of images in magnetism of nanoparticles
• A Fourier slice theorem for magnetic particle imaging using a field-free line
• Computational inverse problems for partial differential equations. Abstracts from the workshop held December 6--12, 2020 (hybrid meeting)
• Dynamic image reconstruction with motion priors in application to three dimensional magnetic particle imaging
• On the degree of ill-posedness of multi-dimensional magnetic particle imaging
• A new 3D model for magnetic particle imaging using realistic magnetic field topologies for algebraic reconstruction
• Model-based reconstruction for magnetic particle imaging in 2D and 3D
• Parameter identification for elliptic boundary value problems: an abstract framework and applications
• Joint super-resolution image reconstruction and parameter identification in imaging operator: analysis of bilinear operator equations, numerical solution, and application to magnetic particle imaging
• On numerical aspects of parameter identification for the Landau-Lifshitz-Gilbert equation in magnetic particle imaging
• Solving inverse problems using data-driven models
• Mathematical modelling and analysis of nanoparticle gradients induced by magnetic fields
• Erratum for Mathematical models for magnetic particle imaging (2018 Inverse Problems 34 083001)

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