Improving the calculation of statistical significance in genome-wide scans

DOI10.1093/biostatistics/kxi025zbMath1169.62361OpenAlexW2105920926WikidataQ51976168 ScholiaQ51976168MaRDI QIDQ3434105

Lars Ängquist, Ola G. Hössjer

Publication date: 23 April 2007

Published in: Biostatistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/biostatistics/kxi025

zbMATH Keywords

Hermite polynomialsNonparametric linkage analysisAdjusted approximation formulaAllele sharingApproximation of distributionsCrossover rateDeviation from NormalityExtreme value formulasGenome-wide significanceMarker density

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40) Genetics and epigenetics (92D10)

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