Modeling the effect of inbreeding among founders in linkage analysis

DOI10.1016/J.TPB.2006.05.004zbMATH Open1101.92032OpenAlexW2021822123WikidataQ42690769 ScholiaQ42690769MaRDI QIDQ851429FDOQ851429

Authors: Ola G. Hössjer 

Publication date: 20 November 2006

Published in: Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.tpb.2006.05.004

Recommendations

• Inverse inbreeding coefficient problems with an application to linkage analysis of recessive diseases in inbred populations
• Missing data methods for linkage analysis of IBS and incomplete IBD from affected sib-pairs
• Determining Inheritance Distributions via Stochastic Penetrances
• scientific article; zbMATH DE number 1305479
• A score test for the linkage analysis of qualitative and quantitative traits based on identity by descent data from sib-pairs

zbMATH Keywords

FoundersHidden Markov algorithmIdentical by descentInbreedingNonparametric linkage analysis

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Problems related to evolution (92D15) Markov processes (60J99)

Cites Work

• Gene Identities and Multiple Relationships
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• The probability that related individuals share some section of genome identical by descent
• Properties of a neutral allele model with intragenic recombination
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• Mapping quantitative trait loci in oligogenic models
• A Class of Tests for Linkage Using Affected Pedigree Members
• Improving the calculation of statistical significance in genome-wide scans
• Recombination as a point process along sequences
• A model for the length of tracts of identity by descent in finite random mating populations
• Asymptotic estimation theory of multipoint linkage analysis under perfect marker information.
• Determining Inheritance Distributions via Stochastic Penetrances
• Conditional likelihood score functions for mixed models in linkage analysis
• Spectral decomposition of score functions in linkage analysis
• A score test for linkage using identity by descent data from sibships
• Computer-simulation methods in human linkage analysis.
• The maximum of a function of a Markov chain and application to linkage analysis
• Using Importance Sampling to Improve Simulation in Linkage Analysis

Cited In (4)

• Inverse inbreeding coefficient problems with an application to linkage analysis of recessive diseases in inbred populations
• Relatedness coefficients in pedigrees with inbred founders
• Determining Inheritance Distributions via Stochastic Penetrances
• Title not available (Why is that?)

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