Modeling the effect of inbreeding among founders in linkage analysis

DOI10.1016/J.TPB.2006.05.004MaRDI QIDQ851429zbMATH OpenOpenAlexWikidataFDO

Authors Ola G. Hössjer

Publication date 20 November 2006

Published in Theoretical Population Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.tpb.2006.05.004

zbMATH Keywords

FoundersHidden Markov algorithmIdentical by descentInbreedingNonparametric linkage analysis

Mathematics Subject Classification ID

Markov processes (60J99) Applications of statistics to biology and medical sciences; meta analysis (62P10) Problems related to evolution (92D15)

Recommendations

• Inverse inbreeding coefficient problems with an application to linkage analysis of recessive diseases in inbred populations
• Missing data methods for linkage analysis of IBS and incomplete IBD from affected sib-pairs
• Determining Inheritance Distributions via Stochastic Penetrances
• scientific article; zbMATH DE number 1305479
• A score test for the linkage analysis of qualitative and quantitative traits based on identity by descent data from sib-pairs

Cites work

• A Class of Tests for Linkage Using Affected Pedigree Members
• A model for the length of tracts of identity by descent in finite random mating populations
• A score test for linkage using identity by descent data from sibships
• Asymptotic estimation theory of multipoint linkage analysis under perfect marker information.
• Computer-simulation methods in human linkage analysis.
• Conditional likelihood score functions for mixed models in linkage analysis
• Determining Inheritance Distributions via Stochastic Penetrances
• Gene Identities and Multiple Relationships
• scientific article; zbMATH DE number 3817476 (Why is no real title available?)
• scientific article; zbMATH DE number 3465127 (Why is no real title available?)
• scientific article; zbMATH DE number 1094276 (Why is no real title available?)
• scientific article; zbMATH DE number 3451202 (Why is no real title available?)
• Improving the calculation of statistical significance in genome-wide scans
• Mapping quantitative trait loci in oligogenic models
• Properties of a neutral allele model with intragenic recombination
• Recombination as a point process along sequences
• Spectral decomposition of score functions in linkage analysis
• The maximum of a function of a Markov chain and application to linkage analysis
• The probability that related individuals share some section of genome identical by descent
• Using Importance Sampling to Improve Simulation in Linkage Analysis

Cited in

(5)

• Inverse inbreeding coefficient problems with an application to linkage analysis of recessive diseases in inbred populations
• scientific article; zbMATH DE number 4084814 (Why is no real title available?)
• scientific article; zbMATH DE number 1305479 (Why is no real title available?)
• Determining Inheritance Distributions via Stochastic Penetrances
• Relatedness coefficients in pedigrees with inbred founders

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