A Class of Tests for Linkage Using Affected Pedigree Members

DOI10.2307/2533202zbMATH Open0824.62100OpenAlexW4300942465WikidataQ46229770 ScholiaQ46229770MaRDI QIDQ4844248FDOQ4844248

Authors: Alice S. Whittemore, Jerry W. Halpern 

Publication date: 13 November 1995

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: https://semanticscholar.org/paper/f113eb4d8e093a41b1f0db1804008a8cc0a184b4

Recommendations

• Global tests for linkage
• Multipoint linkage detection in the presence of heterogeneity
• Combined Association and Linkage Analysis for General Pedigrees and Genetic Models
• Likelihood-Based Inference for the Genetic Relative Risk Based on Affected-Sibling-Pair Marker Data
• Allele-sharing among affected relatives: non-parametric methods for identifying genes

zbMATH Keywords

pedigreegenotypeidentity-by-descentconfiguration probabilityexact \(P\)-valuesmarker allele similaritytests for linkage

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10)

Cited In (37)

• Improving the calculation of statistical significance in genome-wide scans
• Inverse inbreeding coefficient problems with an application to linkage analysis of recessive diseases in inbred populations
• Tests in a Case–control Design Including Relatives
• Title not available (Why is that?)
• The power of linkage analysis of a disease-related endophenotype using asymmetrically ascertained sib pairs
• Asymptotic estimation theory of multipoint linkage analysis under perfect marker information.
• Multipoint linkage detection in the presence of heterogeneity
• Quantifying the fraction of missing information for hypothesis testing in statistical and genetic studies
• Allele-sharing among affected relatives: non-parametric methods for identifying genes
• Multipoint Linkage Analysis Using Affected Relative Pairs and Partially Informative Markers
• Effective sample size: quick estimation of the effect of related samples in genetic case-control association analyses
• A likelihood-based trait-model-free approach for linkage detection of binary trait
• Treatment of Uninformative Families in Mean Allele Sharing Tests for Linkage
• Improving sequence-based genotype calls with linkage disequilibrium and pedigree information
• A score test for linkage using identity by descent data from sibships
• Likelihood-Based Inference for the Genetic Relative Risk Based on Affected-Sibling-Pair Marker Data
• A score test for linkage analysis of ordinal traits based on IBD sharing
• Genetic linkage methods for quantitative traits
• Screening method for genetic linkage analysis: case of the transmission disequilibrium test
• Solution for underflow problem in linkage and segregation analysis
• Combined Association and Linkage Analysis for General Pedigrees and Genetic Models
• Title not available (Why is that?)
• Transmission disequilibrium test (TDT) for a pair of linked marker loci
• The affected sib method. II. The intermediate model
• The power of the N-test of haplotype concordance
• Global tests for linkage
• Most powerful permutation invariant tests for relatedness hypotheses using genotypic data
• Determining Inheritance Distributions via Stochastic Penetrances
• A score test for the linkage analysis of qualitative and quantitative traits based on identity by descent data from sib-pairs
• Solving genetic heterogeneity in extended families by identifying sub-types of complex diseases
• A test of linkage for complex discrete and continuous traits in nuclear families
• Modeling the effect of inbreeding among founders in linkage analysis
• On the combination of transmission/disequilibrium test and mean test for linkage detection using affected sib pairs
• Conditional likelihood score functions for mixed models in linkage analysis
• Information and effective number of meioses in linkage analysis
• Spectral decomposition of score functions in linkage analysis
• Title not available (Why is that?)

This page was built for publication: A Class of Tests for Linkage Using Affected Pedigree Members

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q4844248)