Solving genetic heterogeneity in extended families by identifying sub-types of complex diseases

DOI10.1007/s00180-010-0224-2zbMath1304.65080DBLPjournals/cstat/TayebLBM11OpenAlexW2017201326WikidataQ57537339 ScholiaQ57537339MaRDI QIDQ2513373

Arafat Tayeb, Chantal Mérette, Alexandre Bureau, Aurelie Labbe

Publication date: 28 January 2015

Published in: Computational Statistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00180-010-0224-2

zbMATH Keywords

latent class modelfamilial dependencepedigree peelingtriplet-transmission probability

Mathematics Subject Classification ID

Computational methods for problems pertaining to statistics (62-08)

Uses Software

• SIMLA

Cites Work

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• Identifiability of parameters in latent structure models with many observed variables
• Estimating the dimension of a model
• Latent class and finite mixture models for multilevel data sets
• A Class of Tests for Linkage Using Affected Pedigree Members
• On the Identifiability of Finite Mixtures
• Extension of the SIMLA Package for Generating Pedigrees with Complex Inheritance Patterns: Environmental Covariates, Gene-Gene and Gene-Environment Interaction
• Testing for heterogeneity of recombination fraction values in Human Genetics

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