Extension of the SIMLA Package for Generating Pedigrees with Complex Inheritance Patterns: Environmental Covariates, Gene-Gene and Gene-Environment Interaction

DOI10.2202/1544-6115.1133zbMATH Open1082.92026OpenAlexW1967668456WikidataQ34455632 ScholiaQ34455632MaRDI QIDQ5700518FDOQ5700518

Authors: Mike Schmidt, Elizabeth R. Hauser, Eden R. Martin, Silke Schmidt 

Publication date: 28 October 2005

Published in: Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc1403827

Recommendations

• scientific article; zbMATH DE number 672039
• Semiparametric analysis of complex polygenic gene-environment interactions in case-control studies
• Simulation of data aiming at the estimation of variance components and heritability
• Analyzing Genotype-Environment Data by Mixed Models with Multiplicative Terms
• Simulating realistic zero loop pedigrees using a bipartite Prufer code and graphical modelling
• Combined Association and Linkage Analysis for General Pedigrees and Genetic Models
• Genotype-based association models of complex diseases to detect gene-gene and gene-environment interactions

Mathematics Subject Classification ID

Medical applications (general) (92C50) Genetics and epigenetics (92D10) Software, source code, etc. for problems pertaining to biology (92-04)

Cited In (3)

• SIMLA
• BayesMendel: an R Environment for Mendelian Risk Prediction
• Solving genetic heterogeneity in extended families by identifying sub-types of complex diseases

This page was built for publication: Extension of the SIMLA Package for Generating Pedigrees with Complex Inheritance Patterns: Environmental Covariates, Gene-Gene and Gene-Environment Interaction

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q5700518)