Combined Association and Linkage Analysis for General Pedigrees and Genetic Models

DOI10.2202/1544-6115.1116zbMATH Open1083.62110OpenAlexW2143810650WikidataQ42684294 ScholiaQ42684294MaRDI QIDQ5700510FDOQ5700510

Authors Ola G. Hössjer

Publication date 28 October 2005

Published in Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL http://www.bepress.com/sagmb/vol4/iss1/art11/

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10)

Recommendations

• Conditional likelihood score functions for mixed models in linkage analysis
• Score tests of genetic association in the presence of linkage based on the additive genetic gamma frailty model
• A Class of Tests for Linkage Using Affected Pedigree Members
• Combining dependent tests for linkage or association across multiple phenotypic traits
• Multipoint linkage detection in the presence of heterogeneity

Cited in

(13)

• Combining dependent \(F\)-tests for robust association of quantitative traits under genetic model uncertainty
• A Class of Tests for Linkage Using Affected Pedigree Members
• Combining dependent tests for linkage or association across multiple phenotypic traits
• scientific article; zbMATH DE number 5770594 (Why is no real title available?)
• scientific article; zbMATH DE number 3989153 (Why is no real title available?)
• Allowing for missing genotypes in any members of the nuclear families in transmission disequilibrium test
• scientific article; zbMATH DE number 6001981 (Why is no real title available?)
• Modeling hybrid traits for comorbidity and genetic studies of alcohol and nicotine co-dependence
• Extension of the SIMLA Package for Generating Pedigrees with Complex Inheritance Patterns: Environmental Covariates, Gene-Gene and Gene-Environment Interaction
• The power of generalized odds ratio in assessing association in genetic studies with known mode of inheritance
• Score tests of genetic association in the presence of linkage based on the additive genetic gamma frailty model
• Testing for genetic association in the presence of linkage and gene-covariate interactions
• Conditional likelihood score functions for mixed models in linkage analysis

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