Allowing for missing genotypes in any members of the nuclear families in transmission disequilibrium test

DOI10.1016/J.CSDA.2010.09.004MaRDI QIDQ901491zbMATH OpenOpenAlexFDO

Authors Gülhan Alpargu

Publication date 12 January 2016

Published in Computational Statistics and Data Analysis (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.csda.2010.09.004

zbMATH Keywords

affected offspringincomplete genotypelinkage disequilibriumMendel inheritancetransmission disequilibriumtype 1 diabetes

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10)

Recommendations

• The transmission disequilibrium/heterogeneity test with parental-genotype reconstruction for refined genetic mapping of complex diseases
• Reconstructing parental genotypes when testing for linkage in the presence of association.
• Transmission disequilibrium test (TDT) for a pair of linked marker loci
• Sample sizes for the transmission disequilibrium tests: tdt, s-tdt and 1-tdt
• Tests in a Case–control Design Including Relatives

Cites work

• Combined Association and Linkage Analysis for General Pedigrees and Genetic Models
• scientific article; zbMATH DE number 1834445 (Why is no real title available?)

Cited in

(5)

• Some comments on six inequalities associated with the inefficiency of ordinary least squares with one regressor
• Reconstructing parental genotypes when testing for linkage in the presence of association.
• The transmission disequilibrium/heterogeneity test with parental-genotype reconstruction for refined genetic mapping of complex diseases
• Family-based association analysis in a marker
• scientific article; zbMATH DE number 2204334 (Why is no real title available?)

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