Locally Most Powerful Tests for Detecting Treatment Effects When Only a Subset of Patients Can Be Expected to "Respond" to Treatment

DOI10.2307/2531906MaRDI QIDQ3489335zbMATH OpenOpenAlexWikidataFDO

Authors W. J. Conover, David Salsburg

Publication date 1988

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2307/2531906

zbMATH Keywords

Savage scorestwo-sample rank tests

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited in

(20)

• On using Lehmann alternatives with nonresponders
• Tests for statistical significance of a treatment effect in the presence of hidden sub-populations
• A New u-Statistic with Superior Design Sensitivity in Matched Observational Studies
• Assessing the Effect of the Best Treatment. A Non-parametric Inference Problem
• Two-Sample Rank Tests for Detecting Changes That Occur in a Small Proportion of the Treated Population
• Risk Assessment for Quantitative Responses Using a Mixture Model
• A Locally Most Powerful Test for Detecting a Treatment Effect in the Presence of Nonresponders
• Inference with interference between units in an fMRI experiment of motor inhibition
• Effect Modification and Design Sensitivity in Observational Studies
• Impact of Multiple Matched Controls on Design Sensitivity in Observational Studies
• Weighted M-statistics with superior design sensitivity in matched observational studies with multiple controls
• Sample size calculations for mixture alternatives in a control group vs. treatment group design
• Detection of treatment effects by covariate-adjusted expected shortfall
• Sensitivity Analysis for m‐Estimates, Tests, and Confidence Intervals in Matched Observational Studies
• Detecting sparse heterogeneous mixtures in a two-sample problem
• A New Transformation of Treated-Control Matched-Pair Differences for Graphical Display
• Considerations in testing treatment effects on transient event driven health status changes measured by patient reported outcomes
• A conditioning tactic that increases design sensitivity in observational block designs
• Assessment of statistical significance and clinical relevance
• Mixture normal models in which the proportions of susceptibility are related to dose levels

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