A projection argument for differential inclusions, with applications to persistence of mass-action kinetics

DOI10.3842/SIGMA.2013.025zbMATH Open1279.34031arXiv1208.0874OpenAlexW2168267705WikidataQ115219652 ScholiaQ115219652MaRDI QIDQ352492FDOQ352492

Authors: Manoj Gopalkrishnan, Ezra Miller, Anne Shiu 

Publication date: 4 July 2013

Published in: SIGMA. Symmetry, Integrability and Geometry: Methods and Applications (Search for Journal in Brave)

Abstract: Motivated by questions in mass-action kinetics, we introduce the notion of vertexical family of differential inclusions. Defined on open hypercubes, these families are characterized by particular good behavior under projection maps. The motivating examples are certain families of reaction networks -- including reversible, weakly reversible, endotactic, and strongly endotactic reaction networks -- that give rise to vertexical families of mass-action differential inclusions. We prove that vertexical families are amenable to structural induction. Consequently, a trajectory of a vertexical family approaches the boundary if and only if either the trajectory approaches a vertex of the hypercube, or a trajectory in a lower-dimensional member of the family approaches the boundary. With this technology, we make progress on the global attractor conjecture, a central open problem concerning mass-action kinetics systems. Additionally, we phrase mass-action kinetics as a functor on reaction networks with variable rates.

Full work available at URL: https://arxiv.org/abs/1208.0874

File on IPFS (Hint: this is only the Hash - if you get a timeout, this file is not available on our server.)

Recommendations

• On the persistence and global stability of mass-action systems
• Autocatalysis in reaction networks
• A geometric approach to the global attractor conjecture
• Endotactic Networks and Toric Differential Inclusions
• Polynomial dynamical systems, reaction networks, and toric differential inclusions

zbMATH Keywords

differential inclusionspersistenceglobal attractor conjecturemass-action kineticsreaction network

Mathematics Subject Classification ID

Ordinary differential inclusions (34A60) Global stability of solutions to ordinary differential equations (34D23) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Categorical methods in general topology (54B30) Chemical kinetics in thermodynamics and heat transfer (80A30) Classical flows, reactions, etc. in chemistry (92E20)

Cited In (5)

• Stochastically modeled weakly reversible reaction networks with a single linkage class
• Permanence of Weakly Reversible Mass-Action Systems with a Single Linkage Class
• Convergence to the complex balanced equilibrium for some chemical reaction-diffusion systems with boundary equilibria
• Autocatalysis in reaction networks
• Absolute concentration robustness in networks with low-dimensional stoichiometric subspace

This page was built for publication: A projection argument for differential inclusions, with applications to persistence of mass-action kinetics

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q352492)