Endotactic Networks and Toric Differential Inclusions

DOI10.1137/19M1269312zbMATH Open1461.37077arXiv1906.08384OpenAlexW3048755236MaRDI QIDQ4964243FDOQ4964243

Authors: Gheorghe Craciun, Abhishek Deshpande 

Publication date: 25 February 2021

Published in: SIAM Journal on Applied Dynamical Systems (Search for Journal in Brave)

Abstract: An important dynamical property of biological interaction networks is persistence, which intuitively means that "no species goes extinct". It has been conjectured that dynamical system models of weakly reversible networks (i.e., networks for which each reaction is part of a cycle) are persistent. The property of persistence is also related to the well known global attractor conjecture. An approach for the proof of the global attractor conjecture uses an embedding of weakly reversible dynamical systems into toric differential inclusions. We show that the larger class of endotactic dynamical systems can also be embedded into toric differential inclusions. Moreover, we show that, essentially, endotactic networks form the largest class of networks with this property.

Full work available at URL: https://arxiv.org/abs/1906.08384

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zbMATH Keywords

differential inclusionspermanencepersistencemass-action kineticsreaction networksendotactic networks

Mathematics Subject Classification ID

Dynamical systems in biology (37N25) Toric varieties, Newton polyhedra, Okounkov bodies (14M25) Lattice polytopes in convex geometry (including relations with commutative algebra and algebraic geometry) (52B20) Dynamical aspects of statistical mechanics (37A60) Nonautonomous smooth dynamical systems (37C60) Ordinary differential equations and connections with real algebraic geometry (fewnomials, desingularization, zeros of abelian integrals, etc.) (34C08)

Cites Work

• A computational approach to persistence, permanence, and endotacticity of biochemical reaction systems
• Title not available (Why is that?)
• Introduction to Toric Varieties. (AM-131)
• Mathematical biology. Vol. 2: Spatial models and biomedical applications.
• A Petri net approach to the study of persistence in chemical reaction networks
• Equality relating Euclidean distance cone to positive semidefinite cone
• Structure and stability of certain chemical networks and applications to the kinetic proofreading model of T-cell receptor signal transduction
• Toric dynamical systems
• Global Asymptotic Stability for a Class of Nonlinear Chemical Equations
• Persistence and permanence of mass-action and power-law dynamical systems
• On the persistence and global stability of mass-action systems
• A proof of the global attractor conjecture in the single linkage class case
• A geometric approach to the global attractor conjecture
• The dynamics of weakly reversible population processes near facets
• Catalysis in reaction networks
• Autocatalysis in reaction networks
• Global stability of complex balanced mechanisms
• Robust persistence and permanence of polynomial and power law dynamical systems
• Polynomial Dynamical Systems, Reaction Networks, and Toric Differential Inclusions
• Existence of Positive Steady States for Weakly Reversible Mass-Action Systems
• Permanence of Weakly Reversible Mass-Action Systems with a Single Linkage Class

Cited In (15)

• The Disguised Toric Locus and Affine Equivalence of Reaction Networks
• Endotactic and strongly endotactic networks with infinitely many positive steady states
• A geometric approach to the global attractor conjecture
• Source-Only Realizations, Weakly Reversible Deficiency One Networks, and Dynamical Equivalence
• Tier structure of strongly endotactic reaction networks
• On the connectivity of the disguised toric locus of a reaction network
• The dynamics of weakly reversible population processes near facets
• Quasi-toric differential inclusions
• A lower bound on the dimension of the \(\mathbb{R}\)-disguised toric locus of a reaction network
• A projection argument for differential inclusions, with applications to persistence of mass-action kinetics
• Persistence and permanence of mass-action and power-law dynamical systems
• A computational approach to persistence, permanence, and endotacticity of biochemical reaction systems
• Minimal invariant regions and minimal globally attracting regions for toric differential inclusions
• Minimal invariant regions and minimal globally attracting regions for variable-k reaction systems
• Autocatalytic recombination systems: a reaction network perspective

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