Improving power for testing genetic association in case-control studies by reducing the alternative space

DOI10.1111/J.1541-0420.2009.01241.XMaRDI QIDQ3564583zbMATH OpenOpenAlexWikidataFDO

Authors Jungnam Joo, Minjung Kwak, Gang Zheng

Publication date 26 May 2010

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1111/j.1541-0420.2009.01241.x

zbMATH Keywords

robust teststrend testsgenetic modelsMAXHardy-Weinberg disequilibrium

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10)

Recommendations

• Genetic model selection in two-phase analysis for case-control association studies
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Cites work

• A robust test for two-stage design in genome-wide association studies
• Efficiency Robust Tests for Survival or Ordered Categorical Data
• From Genotypes to Genes: Doubling the Sample Size
• Genetic model selection in two-phase analysis for case-control association studies
• Logistic disease incidence models and case-control studies
• On Robust Procedures
• Some Methods for Strengthening the Common χ 2 Tests
• The Use of Maximin Efficiency Robust Tests in Combining Contingency Tables and Survival Analysis

Cited in

(7)

• Combining dependent \(F\)-tests for robust association of quantitative traits under genetic model uncertainty
• Genetic model selection in two-phase analysis for case-control association studies
• Order-restricted scores test for the evaluation of population-based case-control studies when the genetic model is unknown
• Increasing Power for Tests of Genetic Association in the Presence of Phenotype and/or Genotype Error by Use of Double-Sampling
• Association tests through combining \(p\)-values for case control genome-wide association studies
• An improved robust association test for GWAS with multiple diseases
• Sample size and power analysis for sparse signal recovery in genome-wide association studies

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