Optimizing Restriction Site Placement for Synthetic Genomes

DOI10.1007/978-3-642-13509-5_29zbMATH Open1286.92025OpenAlexW1884601672MaRDI QIDQ3575258FDOQ3575258

Authors: Pablo Montes, Heraldo Memelli, Joondong Kim, Joseph S. B. Mitchell, Charles B. Ward, Steven Skiena 

Publication date: 26 July 2010

Published in: Combinatorial Pattern Matching (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/978-3-642-13509-5_29

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zbMATH Keywords

synthetic biologygenome refactoringrestriction enyzme placement

Mathematics Subject Classification ID

Problem solving in the context of artificial intelligence (heuristics, search strategies, etc.) (68T20) Biochemistry, molecular biology (92C40) Genetics and epigenetics (92D10) Computational difficulty of problems (lower bounds, completeness, difficulty of approximation, etc.) (68Q17) Computational methods for problems pertaining to biology (92-08)

Cited In (3)

• RESCOT: restriction enzyme set and combination optimization tools for rNMP capture techniques
• Optimizing restriction site placement for synthetic genomes
• Codon optimization by 0-1 linear programming

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