Bifurcation analysis of gene regulatory circuits subject to copy number variation

DOI10.1137/090771247MaRDI QIDQ3577830zbMATH OpenOpenAlexWikidataFDO

Authors Yuriy Mileyko, Joshua S. Weitz

Publication date 26 July 2010

Published in SIAM Journal on Applied Dynamical Systems (Search for Journal in Brave)

Full work available at URL http://hdl.handle.net/10161/4315

zbMATH Keywords

bistable feedback circuitcopy number variationgene regulatory networkpositive feedback circuitsaddle-node bifurcationtoggle switch circuit

Mathematics Subject Classification ID

Bifurcation theory for ordinary differential equations (34C23) Qualitative investigation and simulation of ordinary differential equation models (34C60) Bifurcations of singular points in dynamical systems (37G10) Neural networks for/in biological studies, artificial life and related topics (92B20) Genetics and epigenetics (92D10)

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Cited in

(4)

• Bifurcation analysis of a heat-sensitive epigenetic regulatory network
• Dynamic patterns of gene regulation. I: Simple two-gene systems
• Dynamical behavior of the activator-repressor circuit model under random fluctuations
• Influence of gene copy number on self-regulated gene expression

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