Pattern formation through genetic drift at expanding population fronts

DOI10.1142/S0219525910002578MaRDI QIDQ3585117zbMATH OpenOpenAlexFDO

Authors Adnan Ali, S. Grosskinsky

Publication date 19 August 2010

Published in Advances in Complex Systems (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/0912.2241

zbMATH Keywords

annihilating random walksdomain coarseninggenetic driftrange expansiontime-changed Brownian motion

Mathematics Subject Classification ID

Applications of Brownian motions and diffusion theory (population genetics, absorption problems, etc.) (60J70) Monte Carlo methods (65C05) Developmental biology, pattern formation (92C15) Problems related to evolution (92D15)

Abstract: We investigate the nature of genetic drift acting at the leading edge of range expansions, building on recent results in [Hallatschek et al., Proc. Natl. Acad. Sci., extbf{104}(50): 19926 - 19930 (2007)]. A well mixed population of two fluorescently labeled microbial species is grown in a circular geometry. As the population expands, a coarsening process driven by genetic drift gives rise to sectoring patterns with fractal boundaries, which show a non-trivial asymptotic distribution. Using simplified lattice based Monte Carlo simulations as a generic caricature of the above experiment, we present detailed numerical results to establish a model for sector boundaries as time changed Brownian motions. This is used to derive a general one-to-one mapping of sector statistics between circular and linear geometries, which leads to a full understanding of the sectoring patterns in terms of annihilating diffusions.

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Cites work

• Dynamic Scaling of Growing Interfaces
• scientific article; zbMATH DE number 1478492 (Why is no real title available?)
• scientific article; zbMATH DE number 867209 (Why is no real title available?)
• Multi-scaling of the \(n\)-point density function for coalescing Brownian motions
• Universality class of isotropic on-lattice Eden clusters

Cited in

(4)

• Survival in branching cellular populations
• Evolution in range expansions with competition at rough boundaries
• Survival probabilities at spherical frontiers
• Interacting particle systems in time-dependent geometries

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