Explicit and numerical methods for finding optimal therapeutics

DOI10.1016/0270-0255(86)90044-8MaRDI QIDQ3754465zbMATH OpenOpenAlexFDO

Authors Yves Cherruault

Publication date 1986

Published in Mathematical Modelling (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/0270-0255(86)90044-8

zbMATH Keywords

nonlinear systemspharmacokineticsbeta blockersNumerical resultsoptimal therapeuticscompartment model approach

Mathematics Subject Classification ID

Medical applications (general) (92C50) Laplace transform (44A10) Existence theories for optimal control problems involving ordinary differential equations (49J15)

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• Computing optimal properties of drugs using mathematical models of single channel dynamics
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• OptiDose: computing the individualized optimal drug dosing regimen using optimal control
• Parameters identification and optimal control in pharmacokinetics
• Optimal drug administration for the control of certain cholesterol fats in the blood system
• Forming a therapeutic sphere to treat ailments using optimization techniques
• Simulation of optimal infusion rate input. II
• Numerical solution of a drug displacement problem with bounded state variables
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