Explicit and numerical methods for finding optimal therapeutics

DOI10.1016/0270-0255(86)90044-8zbMATH Open0617.92002OpenAlexW1973486516MaRDI QIDQ3754465FDOQ3754465

Authors: Yves Cherruault 

Publication date: 1986

Published in: Mathematical Modelling (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0270-0255(86)90044-8

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zbMATH Keywords

nonlinear systemspharmacokineticsbeta blockersNumerical resultsoptimal therapeuticscompartment model approach

Mathematics Subject Classification ID

Medical applications (general) (92C50) Laplace transform (44A10) Existence theories for optimal control problems involving ordinary differential equations (49J15)

Cited In (12)

• Numerical treatment of cardiac diseases using optimal control theory
• Modeling the action of drugs on cellular enzymes by means of optimal control techniques
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• Optimization of drugs' action using minimization methods
• On the role of the objective in the optimization of compartmental models for biomedical therapies
• Optimal drug administration for the control of certain cholesterol fats in the blood system
• Parameters identification and optimal control in pharmacokinetics
• Forming a therapeutic sphere to treat ailments using optimization techniques
• Computing optimal properties of drugs using mathematical models of single channel dynamics
• Numerical solution of a drug displacement problem with bounded state variables
• A pharmacokinetical control model of pathologic processes
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