A statistical approach to the inverse problem in magnetoencephalography
From MaRDI portal
Publication:400666
DOI10.1214/14-AOAS716zbMATH Open1454.62424arXiv1401.2395MaRDI QIDQ400666FDOQ400666
Authors: Zhigang Yao, William F. Eddy 
Publication date: 22 August 2014
Published in: The Annals of Applied Statistics (Search for Journal in Brave)
Abstract: Magnetoencephalography (MEG) is an imaging technique used to measure the magnetic field outside the human head produced by the electrical activity inside the brain. The MEG inverse problem, identifying the location of the electrical sources from the magnetic signal measurements, is ill-posed, that is, there are an infinite number of mathematically correct solutions. Common source localization methods assume the source does not vary with time and do not provide estimates of the variability of the fitted model. Here, we reformulate the MEG inverse problem by considering time-varying locations for the sources and their electrical moments and we model their time evolution using a state space model. Based on our predictive model, we investigate the inverse problem by finding the posterior source distribution given the multiple channels of observations at each time rather than fitting fixed source parameters. Our new model is more realistic than common models and allows us to estimate the variation of the strength, orientation and position. We propose two new Monte Carlo methods based on sequential importance sampling. Unlike the usual MCMC sampling scheme, our new methods work in this situation without needing to tune a high-dimensional transition kernel which has a very high cost. The dimensionality of the unknown parameters is extremely large and the size of the data is even larger. We use Parallel Virtual Machine (PVM) to speed up the computation.
Full work available at URL: https://arxiv.org/abs/1401.2395
Recommendations
- Quantifying time-varying sources in magnetoencephalography -- a discrete approach
- State-space solutions to the dynamic magnetoencephalography inverse problem using high performance computing
- Particle filters for magnetoencephalography
- Sequential Monte Carlo samplers for semi-linear inverse problems and application to magnetoencephalography
- Bayesian multi-dipole modelling of a single topography in MEG by adaptive sequential Monte Carlo samplers
Computational methods for problems pertaining to statistics (62-08) Applications of statistics to biology and medical sciences; meta analysis (62P10) Biomedical imaging and signal processing (92C55)
Cites Work
- Inference from iterative simulation using multiple sequences
- Sequential Monte Carlo Samplers
- On Gibbs sampling for state space models
- Likelihood analysis of non-Gaussian measurement time series
- Sequential Monte Carlo Methods for Dynamic Systems
- Simulation Run Length Control in the Presence of an Initial Transient
- Markov chain Monte Carlo for dynamic generalised linear models
- Title not available (Why is that?)
- The time to the ancestor along sequences with recombination
- Dynamic Conditional Independence Models and Markov Chain Monte Carlo Methods
- Dynamic filtering of static dipoles in magnetoencephalography
- Conditional Prior Proposals in Dynamic Models
- Non-stationary magnetoencephalography by Bayesian filtering of dipole models
- Title not available (Why is that?)
- A Rao–Blackwellized particle filter for magnetoencephalography
Cited In (21)
- A hierarchical Krylov-Bayes iterative inverse solver for MEG with physiological preconditioning
- An approach to the inverse problem of brain functional mapping under the assumption of gamma distributed myogram noise within rest intervals using the independent component analysis
- Solving the inverse magnetoencephalography problem in the multidipole model
- Statistical Inference for the Effect of Magnetic Brain Stimulation on a Motoneurone
- Sequential Monte Carlo samplers for semi-linear inverse problems and application to magnetoencephalography
- Conditionally Gaussian Hypermodels for Cerebral Source Localization
- Parallel optimization applied to magnetoencephalography
- A two-way regularization method for MEG source reconstruction
- Estimating the number of sources in magnetoencephalography using spiked population eigenvalues
- Quantifying time-varying sources in magnetoencephalography -- a discrete approach
- An inversion method based on random sampling for real-time MEG neuroimaging
- Inverse modeling for MEG/EEG data
- Bayesian multi-dipole modelling of a single topography in MEG by adaptive sequential Monte Carlo samplers
- The solution of the biomagnetic inverse problem by maximum statistical entropy
- A Comparative Study Of Global Optimization Approaches To Meg Source Localization
- State-space solutions to the dynamic magnetoencephalography inverse problem using high performance computing
- Title not available (Why is that?)
- Bayesian preconditioned CGLS for source separation in MEG time series
- Magnetoencephalography source localization using improved simplex method
- Particle filters for magnetoencephalography
- Magnetoencephalography inverse problem for spherical and spheroid models
Uses Software
This page was built for publication: A statistical approach to the inverse problem in magnetoencephalography
Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q400666)
