scientific article; zbMATH DE number 108273

MaRDI QIDQ4023731zbMATH OpenFDO

Authors Thomas W. Lohmann

Publication date 23 January 1993

zbMATH Keywords

approximate covariance matrixconstrained nonlinear least squares problemsGauss-Newton methodinformation matricesnumerically stable computationoptimal experimental designparameter estimatesstatistical analysistest examples

Mathematics Subject Classification ID

Optimal statistical designs (62K05) Probabilistic methods, stochastic differential equations (65C99)

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• A differentiable reformulation for E-optimal design of experiments in nonlinear dynamic biosystems
• Structure exploiting parameter estimation and optimum experimental design methods and applications in microbial enhanced oil recovery
• Experimental design and inverse problems in plant biological modeling

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