scientific article; zbMATH DE number 148942

MaRDI QIDQ4031333zbMATH OpenFDO

Authors Andrzej Świerniak, Zdzisław Duda

Publication date 1 April 1993

zbMATH Keywords

singularitycancer chemotherapybilinear modelsdrug activityGompertz-type growthreaction of critical normal tissuessingular control solutions

Mathematics Subject Classification ID

Medical applications (general) (92C50) Differential games and control (49N70) Pursuit and evasion games (49N75) Existence theories for optimal control problems involving ordinary differential equations (49J15)

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Cited in

(6)

• Optimal control problems for the Gompertz model under the Norton-Simon hypothesis in chemotherapy
• Singularity of optimal control in some problems related to optimal chemotherapy
• ANALYSIS OF A CELL-CYCLE SPECIFIC MODEL FOR CANCER CHEMOTHERAPY
• Singularity of controls in a simple model of acquired chemotherapy resistance
• Singular controls and chattering arcs in optimal control problems arising in biomedicine
• Catalog of the optimal controls in cancer chemotherapy for the Gompertz model depending on PK/PD and the integral constraint

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