A mathematical model for the effects of HER2 over-expression on cell cycle progression in breast cancer

DOI10.1007/s11538-011-9663-3zbMath1402.92149OpenAlexW2131060291WikidataQ39495449 ScholiaQ39495449MaRDI QIDQ417285

Amina Eladdadi, David Isaacson

Publication date: 14 May 2012

Published in: Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s11538-011-9663-3

zbMATH Keywords

mathematical modelingcell proliferationbreast cancercell cycleEGFRHER2HER2 over-expressionreceptor modeling

Mathematics Subject Classification ID

Medical applications (general) (92C50) Cell biology (92C37)

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Cites Work

• A history of the study of solid tumour growth: the contribution of mathematical modelling
• Modelling the flow of cytometric data obtained from unperturbed human tumour cell lines: parameter fitting and comparison
• A theoretical analysis of interval drug dosing for cell-cycle-phase- specific drugs
• Necessary and sufficient conditions for asynchronous exponential growth in age structured cell populations with quiescence
• A mathematical model for the effects of HER2 overexpression on cell proliferation in breast cancer
• Analysis of a molecular structured population model with possible polynomial growth for the cell division cycle
• A generalised age- and phase-structured model of human tumour cell populations both unperturbed and exposed to a range of cancer therapies

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