Theorems and application of local activity of CNN with five state variables and one port
Reaction-diffusion equations (35K57) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Computational methods for problems pertaining to biology (92-08) Neural networks for/in biological studies, artificial life and related topics (92B20) Developmental biology, pattern formation (92C15)
Summary: Coupled nonlinear dynamical systems have been widely studied recently. However, the dynamical properties of these systems are difficult to deal with. The local activity of cellular neural networks (CNNs) has provided a powerful tool for studying the emergence of complex patterns in a homogeneous lattice, which is composed of coupled cells. In this paper, the analytical criteria for the local activity in reaction-diffusion CNNs with five state variables and one port are presented, which consist of four theorems, including a serial of inequalities involving CNN parameters. These theorems can be used for calculating the bifurcation diagrams to determine or analyze the emergence of complex dynamic patterns, such as chaos. As a case study, a reaction-diffusion CNN of the hepatitis B Virus (HBV) mutation-selection model is analyzed and simulated, and the bifurcation diagram is calculated. Using the diagram, numerical simulations of this CNN model provide reasonable explanations of complex mutant phenomena during therapy. Therefore, it is demonstrated that the local activity of CNNs provide a practical tool for the complex dynamics study of some coupled nonlinear systems.
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