The Behavior of the P-Value When the Alternative Hypothesis is True

DOI10.2307/2533093MaRDI QIDQ4349996zbMATH OpenOpenAlexWikidataFDO

Authors H. M. James Hung, R. T. O'Neill, Peter Bauer, K. Köhne

Publication date 27 August 1997

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2307/2533093

zbMATH Keywords

clinical trialsmeta-analysispowersignificance\(P\)-value distributionphyp plot

Mathematics Subject Classification ID

Parametric hypothesis testing (62F03) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited in

(19)

• An evaluation of statistical methods for aggregate patterns of replication failure
• A parametric meta-analysis
• Two useful distributions for Bayesian predicitve procedures under normal models
• A semiparametric mixture method for local false discovery rate estimation from multiple studies
• Simultaneous control of false positives and false negatives in multiple hypotheses testing
• Bias-corrected estimators for proportion of true null hypotheses: application of adaptive FDR-controlling in segmented failure data
• Interval estimation in a finite mixture model: Modeling \(P\)-values in multiple testing ap\-plications
• Utilities of the \(P\)-value distribution associated with effect size in clinical trials
• Reconnecting p-Value and Posterior Probability Under One- and Two-Sided Tests
• \(p\)-values as expert votes
• Characterization of the distribution of \(p\)-values of parametric tests in normal populations
• Estimating the proportion of true null hypotheses with application in microarray data
• Augmenting leakage detection using bootstrapping
• Advantages of variance stabilization
• Floating prioritized subset analysis: A powerful method to detect differentially expressed genes
• Sample size for simultaneous testing of rate differences in non-inferiority trials with multiple endpoints
• Beyond the two-trials rule
• AN ADAPTIVE PROCEDURE FOR GOODNESS-OF-FIT BASED ON SAMPLE SPACINGS
• NetMix: a network-structured mixture model for reduced-bias estimation of altered subnetworks

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