NetMix: a network-structured mixture model for reduced-bias estimation of altered subnetworks

DOI10.1007/978-3-030-45257-5_11MaRDI QIDQ5040358zbMATH OpenOpenAlexFDO

Authors Matthew A. Reyna, Uthsav Chitra, Rebecca Elyanow, Benjamin J. Raphael

Publication date 14 October 2022

Published in Lecture Notes in Computer Science (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/978-3-030-45257-5_11

zbMATH Keywords

cancermaximum likelihood estimationgene expressioninteraction networksnetwork anomaly

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Protein sequences, DNA sequences (92D20) Systems biology, networks (92C42) Computational methods for problems pertaining to biology (92-08)

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• NetMix2: unifying network propagation and altered subnetworks
• Differentially Mutated Subnetworks Discovery
• Estimation of multiple networks in Gaussian mixture models
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Cites work

• scientific article; zbMATH DE number 3567782 (Why is no real title available?)
• A spatial scan statistic
• Adaptive multiscale detection of filamentary structures in a background of uniform random points
• Consistency of the MLE under mixture models
• Detecting Anomalous Activity on Networks With the Graph Fourier Scan Statistic
• Detection of an anomalous cluster in a network
• Distribution-free detection of structured anomalies: permutation and rank-based scans
• On combinatorial testing problems
• Scan statistics
• Searching for a trail of evidence in a maze
• The Behavior of the P-Value When the Alternative Hypothesis is True

Cited in

(2)

• Sub-modular resolution analysis by network mixture models
• NetMix2: unifying network propagation and altered subnetworks

Describes a project that uses

Uses Software

• NetSig
• NetMix2
• HotNet
• PathBLAST
• Cytoscape

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