A combined p-value approach to infer pathway regulations in eQTL mapping

DOI10.4310/SII.2011.V4.N3.A13zbMATH Open1245.62146OpenAlexW2165148665MaRDI QIDQ440339FDOQ440339

Authors: Shaoyu Li, Barry L. Williams, Yuehua Cui 

Publication date: 18 August 2012

Published in: Statistics and Its Interface (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.4310/sii.2011.v4.n3.a13

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zbMATH Keywords

gene regulation

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10) Systems biology, networks (92C42)

Cited In (14)

• More powerful genetic association testing via a new statistical framework for integrative genomics
• Statistical inference of genetic pathway analysis in high dimensions
• Statistical independence of the colocalized association signals for type 1 diabetes and RPS26 gene expression on chromosome 12q13
• Regression-based multi-trait QTL mapping using a structural equation model
• Pathway-based kernel boosting for the analysis of genome-wide association studies
• Nonparametric pathway-based regression models for analysis of genomic data
• Network assisted analysis to reveal the genetic basis of autism
• Integrative analysis of genetical genomics data incorporating network structures
• Discussion: Why do we test multiple traits in genetic association studies?
• A statistical framework for eQTL mapping using RNA-seq data
• Molecular QTL discovery incorporating genomic annotations using Bayesian false discovery rate control
• Causal graphical models in systems genetics: a unified framework for joint inference of causal network and genetic architecture for correlated phenotypes
• Using partial correlation coefficient algorithm to excavate pathway genes in genetic interaction data
• A covariance-enhanced approach to multitissue joint eQTL mapping with application to transcriptome-wide association studies

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