A combined p-value approach to infer pathway regulations in eQTL mapping

DOI10.4310/SII.2011.V4.N3.A13MaRDI QIDQ440339zbMATH OpenOpenAlexFDO

Authors Shaoyu Li, Barry L. Williams, Yuehua Cui

Publication date 18 August 2012

Published in Statistics and Its Interface (Search for Journal in Brave)

Full work available at URL https://doi.org/10.4310/sii.2011.v4.n3.a13

zbMATH Keywords

gene regulation

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10) Systems biology, networks (92C42)

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Cited in

(14)

• More powerful genetic association testing via a new statistical framework for integrative genomics
• Statistical inference of genetic pathway analysis in high dimensions
• Statistical independence of the colocalized association signals for type 1 diabetes and RPS26 gene expression on chromosome 12q13
• Regression-based multi-trait QTL mapping using a structural equation model
• Pathway-based kernel boosting for the analysis of genome-wide association studies
• Network assisted analysis to reveal the genetic basis of autism
• Nonparametric pathway-based regression models for analysis of genomic data
• Integrative analysis of genetical genomics data incorporating network structures
• Discussion: Why do we test multiple traits in genetic association studies?
• A statistical framework for eQTL mapping using RNA-seq data
• Molecular QTL discovery incorporating genomic annotations using Bayesian false discovery rate control
• Causal graphical models in systems genetics: a unified framework for joint inference of causal network and genetic architecture for correlated phenotypes
• Using partial correlation coefficient algorithm to excavate pathway genes in genetic interaction data
• A covariance-enhanced approach to multitissue joint eQTL mapping with application to transcriptome-wide association studies

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